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  ササキ　ユカ
  佐々木　由香   歯学部 歯学科   講師
■ 最終学歴・学位
1. 長浜バイオ大学大学院 バイオサイエンス研究科 博士課程修了 博士（バイオサイエンス）
■ 著書
1. 現代歯科薬理学 第7版（第10章）  2024/01
2. 現代歯科薬理学 第7版（第15章）  2024/01
■ 学術研究論文
1. NSC-3852 synergistically enhances the cytotoxicity of olaparib in oral squamous cell carcinoma  2025/01
2. Activated NAD+ biosynthesis pathway induces olaparib resistance in BRCA1 knockout pancreatic cancer cells  2024/04
3. Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells.  2023/11
4. PARP1 regulates cellular processes mediated by exosomal miRNAs in dental pulp stem cells.  2021/09
5. A Combination of GM-CSF and Released Factors from Gamma-Irradiated Tumor Cells Enhances the Differentiation of Macrophages from Bone Marrow Cells and Their Antigen-Presenting Function and Polarization to Type 1.  2021/07
6. A newly established monoclonal antibody against ERCC1 detects major isoforms of ERCC1 in gastric cancer  2021/08
7. The Induction of Parathyroid Cell Differentiation from Human Induced Pluripotent Stem Cells Promoted Via TGF-α/EGFR Signaling  2023/11
8. Singlet-oxygen photosensitizers with a tetrad structure and a single BODIPY chromophore: An evidence for transition state stabilization of intersystem crossing  2023/02
9. Radiosensitization to γ-ray by functional inhibition of APOBEC3G  2022/05
10. PARP inhibitor decreases Akt phosphorylation and induces centrosome amplification and chromosomal aneuploidy in CHO-K1 cells  2022/05
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■ 学会発表
1. High NAD+ levels by activation of NAD+ synthesis pathway induces resistance to PARP inhibitors in BRCA1 knockout pancreatic cancer cells.（口頭発表，一般）  2025/03/19
2. High intracellular NAD+ levels induce multidrug resistance including PARP inhibitors in BRCA1 knockout pancreatic cancer cells.（ポスター，一般）  2025/02/03
3. PARG阻害薬は破骨細胞分化を抑制する（ポスター，一般）  2024/07/21
4. Dysfunction of dual specificity phosphatase 22 (DUSP22) and poly(ADP-ribose) glycohydrolase (PARG) induces synthetic lethal effects in lung cancer cell lines.（ポスター，一般）  2021/09/08
5. Profiles of extracellular release of HMGB1 in cells and a xenograft model of boron neutron capture reaction（ポスター，一般）  2024/11/06
6. Activated NAD+ biosynthesis pathway induces resistance to PARP inhibitors in BRCA1 knockout pancreatic cancer cells.（ポスター，一般）  2024/09/20
7. PARP inhibitors enhance abscopal effect of BNCT through GM-CSF action（ポスター，一般）  2024/07/26
8. The role of GM-CSF in the early response to BNCT（口頭発表，一般）  2024/06/22
9. PARP阻害薬olaparibの効果を増感する化合物の探索（口頭発表，一般）  2024/04/13
10. 低濃度のConnarus ruber 抽出液はグリセルアルデヒドの細胞毒性に対して阻害効果を持つ（口頭発表，一般）  2024/04/13
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